Advancing Lymphodepletion-Free CAR-Ts to Transform Autoimmune Disease Treatment

  • Examine how lymphodepletion impacts trial design, patient safety, and overall therapeutic outcomes in autoimmune indications
  • Explore strategies to improve monitoring, immunogenicity assessment, and product development for lymphodepletion-free CAR-Ts
  • Highlight emerging approaches to optimise persistence and efficacy without reliance on toxic preconditioning regimens