James Arnold
Company: Korecyte Bio
Job title: CSO
Seminars:
Hypoxia-Sensing CAR-T Cells for Treating Solid Cancers 2:15 pm
Introducing ‘HypoxiCAR’ a CAR-T platform which responds to hypoxia, a characteristic of most solid cancers, to express CAR molecules selectively in the tumour microenvironment We demonstrate the HypoxiCAR platform to be a sensitive and dynamic safety switch We demonstrate that hypoxia-sensing CAR-T cells effectively avoid the toxicities associated with on-target off-tumour activation in healthy tissues…Read more
day: Day 2 - Track A - PM