Adrian Bot, MD, PhD

Company: Capstan Therapeutics
Job title: Chief Scientific Officer and Executive Vice President, R&D
Seminars:
Panel Discussion: Exploring the Opportunities for Cell Therapies to Treat Indications Beyond Oncology 12:30 pm
• Do cell therapies have the potential to treat non-oncology indications? I.e. autoimmune disorders, infections, fibrosis and more • What are the main scientific challenges that lie ahead? • How do we navigate the regulatory landscape?Read more
day: Day 2 - Track B - Morning
Workshop A: In Vivo Production of Functional CAR-T Cells by mRNA Targeted Lipid Nanoparticles 9:00 am
Targeted lipid nanoparticles can effectively reprogramme T-cells in vivo to express a CAR CAR-T cells produced in this manner are functional and can ameliorate pathologyRead more
day: Workshop - Track A - Morning
Paving the Way to In Vivo Programming of the Immune System 2:00 pm
• Exploring challenges and lessons learned from ex vivo cell therapy: efforts to date showed that ex vivo genetically engineered T-cells can mediate profound clinical efforts in select patient populations; however, deep translational analysis pointed to mechanisms of treatment resistance and toxicities that represent an access barrier • Leveraging in vivo reprogramming of the immune…Read more
day: Day 2 - Track A - Afternoon
Chair’s Opening Remarks 8:20 am
day: Day One