Luca Gattinoni

Company: Leibniz Institute for Immunotherapy

Job title: Professor, Chair for Functional Immune Cell Modulation


Reprogramming T Cell Fate and Antitumor Function by MicroRNA Therapeutics 5:00 pm

• Overexpression of miR-155 enhances homeostatic cytokine signaling overcoming the need of lymphodepletion preconditioning. • miR-155 modulates T cell epigenetic circuitry to restrict terminal differentiation and functional exhaustion. • A human miR-155 SNP boost CAR T cell polyfunctionality and antitumor responses more effectively than its wild-type counterpartRead more

day: Day 1 – Track A – Evening

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