Maintaining Both Innate Killing & Specific Targeting of Heterogeneous Tumours with Chemotherapy-Resistant Chlorotoxin CAR-T Cells

Time: 10:45 am
day: Day 2 - Track B - Morning


  • Tumour heterogeneity can be addressed by upregulating broadly-expressed stress-induced surface antigens with chemotherapy and targeting these antigens with chemotherapy-resistant cells
  • We will discuss the use of Chlorotoxin to improve delivery of CAR-T cells to the tumour site while maintaining their multiple tumour cytolytic functions.
  • Supercharging optimisation and translation of allogeneic products