Workshop I: Improving T-Cell Function with Epigenetic & Genetic Reprogramming to Improve Cell Therapy Outcomes in Solid Tumours

Time: 3:00 pm
day: Workshop – Track C – Evening


  • Epigenetic reprogramming (Epi-R) results in durable stemness of T-cells
  • Genetic reprogramming (Gen-R) limits T-cell exhaustion after infusion to reverse the suppressive effects of the tumour microenvironment and continuous antigen stimulation
  • These technologies are being evaluated in all T-cell modalities, CAR-T cells (CAR), TCR engineered T-cells (TCR), and tumour infiltrating lymphocytes (TIL) products