Engineering TCR & CAR-T Cells Through Hematopoietic Stem Cells

Time: 12:00 pm
day: Focus Day - Track A - Afternoon


  • Engineering blood forming (hematopoietic) progenitors with TCRs or CARs to target chronic viral infection or malignancies to create an infinite source of T-cells
  • Demonstrating long-term benefit and T-cell persistence in humanised mice and nonhuman primate models
  • Demonstration of safety and efficacy and the next steps in clinical translation